Let's put it like this. The character in the above picture is Mina.

By the author's own admission, she's one of the characters he's been most interested to get going.

This statement was made by the author in 2015. Since 2015, Mina's importance to the plot not counting things the cast as a whole was involved in has been-

-showed up in a character's backstory for a few pages

-fought a villain and choked so she could get rescued by the character whose backstory she appeared in

…That's it.

So to answer your question. No, no they don't.