Notes:

My edit using scenes from Tourettes Guy videos, all from the original 4-part "best of" series on the official YouTube channel.
Scenes by panel:
Top left: coming out of the bathroom drunk from part 1
Top right: listening to Shirlena talk about her mother from part 3
Bottom left: looking for a bathroom in the back of a store from part 4
Bottom right: falling out of bed after waking up to a giant M&M from part 1